Acetonitrile is a solvent also known as methyl cyanide, cyanomethane, and ethanenitrile. It is colorless, volatile (bp 82 °C), flammable (flash point 2 °C), and toxic. It is miscible with water and most organic solvents except for some saturated hydrocarbons.
Is acetonitrile a VOC?
It is an aliphatic nitrile and a volatile organic compound. Acetonitrile has many uses, including as a solvent, for spinning fibers, and in lithium batteries. It is primarily found in air from automobile exhaust and manufacturing facilities.
What is the most common VOC?
Here is a list of common volatile organic compunds:
- Acetic Acid. …
- Butanal. …
- Carbon Disulfide. …
- Ethanol. …
- Alcohol. …
- Formaldehyde. …
- Methylene Chloride. Also known as dichloromethane, this is one of the most common VOCs. …
- Living With VOCs. Unfortunately, VOCs are a part of life, and there are too many of them to list.
Is acetonitrile poisonous?
Acetonitrile is a toxic, colorless liquid with an ether-like odor and a sweet, burnt taste. It is an extremely dangerous substance and must be handled with caution as it can cause severe health effects and/or death.
Is acetone and acetonitrile the same?
The key difference between acetonitrile and acetone is that acetonitrile is a nitrile compound, whereas acetone is a ketone. Acetonitrile is an organic compound having the chemical formula CH3CN while Acetone is an organic compound having the chemical formula (CH3)2CO. … Acetone is important as a polar solvent.
What is the pH of acetonitrile?
The pH 19 in acetonitrile corresponds by its acidity pretty well to pH 7 in water.
How do you make acetonitrile?
Mixing aqueous solution of ammonium acetate and gaseous ammonia, preheating and making the mixture enter a fixed bed reactor which is filled with a catalyst aluminium oxide for reaction to generate acetonitrile which containing mixed gas, after continuously refining the gas we got pure Acetonitrile.
How do you remove acetonitrile from a compound?
The easiest way is using a PTFE coated, -84C lyophilize. In this way, you can directly freeze dry water/ACN. Afterwards, you can try secondary drying at elevated temperature to remove bounded water.
Why is acetonitrile used in HPLC?
Acetonitrile is often used because of its low UV cutoff, lower viscosity (methanol forms highly viscous mixtures with water at certain concentrations), and higher boiling point.
Why is acetonitrile used as a solvent?
Since the lower the absorbance of an organic solvent used for mobile phases, the lower the noise in UV detection, the LC grade acetonitrile is best suited for high sensitivity analysis at short UV wavelengths. Also, the LC grade acetonitrile results in less ghost peaking for gradient baselines.
How do you dry acetonitrile?
Acetonitrile and acetone can be dried over P4O10 to remove trace amounts of water. In the presence of larger amounts of water, these compounds form condensation products and have to be pre-dried with Calcium hydride. Other procedures involve the use of anhydrous magnesium sulfate (dimethyl formamide, DMF).
What is acetonitrile used for?
Acetonitrile is a colorless liquid with an Ether-like odor. It is used as a solvent, and in making pesticides, pharmaceuticals, batteries and rubber products.
What is the other name of acetone?
Acetone (CH3COCH3), also called 2-propanone or dimethyl ketone, organic solvent of industrial and chemical significance, the simplest and most important of the aliphatic (fat-derived) ketones.
Is acetonitrile a carcinogen?
No data are available on its carcinogenic effects in humans; EPA has classified it as a Group D, not classifiable as to human carcinogenicity. Cancer Risk: No pertinent data concerning the carcinogenicity of acetonitrile in humans were located.
What happens if you get acetonitrile on your skin?
Acetonitrile is severely irritating to the eyes and slightly irritating to the skin. Prolonged contact can lead to absorption through the skin and more intense irritation. Acetonitrile is regarded as having adequate warning properties.
How much acetonitrile is toxic?
Acetonitrile has a TLV-TWA of 40 ppm (67 mg/m3), with a short-term exposure limit (STEL) of 60 ppm (101 mg/m3), recommended to protect against organic cyanide poisoning and injury to the respiratory tract (ACGIH, 1991).
How do you handle acetonitrile?
Keep the container tightly sealed. Use a fume hood to minimise exposure to this substance. Wear protective clothing to avoid skin or eye contact, inhalation or ingestion. A long sleeved laboratory coat or gown, rubber gloves, safety goggles and a face mask as a minimum standard.